In a large mixing bowl, combine the sliced cucumbers, edamame, and red onion.
In a small bowl, whisk together the toasted sesame oil, rice vinegar, soy sauce, honey, neutral oil, grated ginger, and minced garlic until well combined.
Pour the dressing over the cucumber mixture in the large bowl.
Gently toss everything together until all ingredients are evenly coated with the dressing.
Let the salad sit at room temperature for about 10 minutes to allow the flavors to meld.
Just before serving, sprinkle the toasted sesame seeds over the top and give it one final gentle toss.
Taste and adjust seasoning with salt and pepper if needed.